Question 1

Use the following pedigree (Figure 11.3)  for a family in which dark-shaded symbols represent individuals with one of the two major types of colon cancer. Numbers under the symbols are the individual's age at the time of diagnosis. A slash through the symbol indicates that the individual is deceased.  Figure 11.3
-In each generation of this family after generation I, the age at diagnosis is significantly lower than would be found in nonfamilial (sporadic)  cases of this cancer (~63 years) . What is the most likely reason?

Accepted Answer

A)   Members of this family know to be checked for colon cancer early in life.
B)   Hereditary (or familial)  cases of this cancer typically occur at earlier ages than do nonfamilial forms.
C)   This is pure chance; it would not be expected if you were to look at a different family.
D)   This cancer requires mutations in more than this one gene.
E)   Affected members of this family are born with colon cancer, and it can be detected whenever they are first tested.F) A) and D)
G) A) and E)

Question 2

Please use the following information to answer the question(s)  below.
A man who is an achondroplastic dwarf with normal vision marries a color-blind woman of normal height. The man's father was 6 feet tall, and both the woman's parents were of average height. Achondroplastic dwarfism is autosomal dominant, and red-green color blindness is X-linked recessive.
-How many unique gametes could be produced through independent assortment by an individual with the genotype AaBbCCDdEE?

Accepted Answer

A)   4
B)   8
C)   16
D)   64E) None of the above
F) A) and B)

Question 3

Please use the following information to answer the question(s)  below.
A man who is an achondroplastic dwarf with normal vision marries a color-blind woman of normal height. The man's father was 6 feet tall, and both the woman's parents were of average height. Achondroplastic dwarfism is autosomal dominant, and red-green color blindness is X-linked recessive.
-A scientist discovers a DNA-based test for one allele of a particular gene. This and only this allele, if homozygous, produces an effect that results in death at or about the time of birth. Which of the following statements describes the best use of this discovery?

Accepted Answer

A)   Screen all newborns of an at-risk population.
B)   Design a test for identifying heterozygous carriers of the allele.
C)   Introduce a normal allele into deficient newborns.
D)   Follow the segregation of the allele during meiosis.E) None of the above
F) A) and B)

Exam 11: Mendel and the Gene Idea

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Exam 11: Mendel and the Gene Idea

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