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The first step of β oxidation is a(n) ________________-linked oxidation of the fatty acyl chain.

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________________ from fatty acid oxidation may enter glycolysis after phosphorylation and oxidation.

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The enzyme ____________ is activated by hormones and is responsible for the first hydrolysis of triacylglycerol.


A) pyrophosphate
B) 106 ATP
C) pyruvate dehydrogenase
D) β oxidation
E) glucagon
F) glycolysis
G) 30 ATP
H) cobalamin
I) β hydroxybutyrate
J) hormone-sensitive lipase
K) oxaloacetate
L) adipose
M) acyl CoA dehydrogenase

N) F) and H)
O) E) and J)

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Coenzyme(s) involved in the degradation of saturated fatty acyl CoA include(s) :


A) FAD.
B) NAD+.
C) TPP.
D) A and B.
E) A, B, and C.

F) A) and E)
G) B) and E)

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Untreated, chronic ketone body production will ________________ blood pH levels.

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Why is the anhydrous nature of triacylglycerols important in energy efficiency?

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Carbohydrates need to be hydrated to be ...

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The enzyme acyl CoA synthetase catalyzes:


A) lipolysis to release free glyceraldehyde.
B) ATP-dependent reduction prior to activation.
C) ATP-dependent activation of fatty acids using CoA.
D) All of the above.
E) None of the above.

F) A) and D)
G) B) and E)

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The transfer of an acyl group to coenzyme A is driven by the hydrolysis of ____________.


A) pyrophosphate
B) 106 ATP
C) pyruvate dehydrogenase
D) β oxidation
E) glucagon
F) glycolysis
G) 30 ATP
H) cobalamin
I) β hydroxybutyrate
J) hormone-sensitive lipase
K) oxaloacetate
L) adipose
M) acyl CoA dehydrogenase

N) A) and J)
O) A) and M)

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Another name for vitamin B12 is ____________.


A) pyrophosphate
B) 106 ATP
C) pyruvate dehydrogenase
D) β oxidation
E) glucagon
F) glycolysis
G) 30 ATP
H) cobalamin
I) β hydroxybutyrate
J) hormone-sensitive lipase
K) oxaloacetate
L) adipose
M) acyl CoA dehydrogenase

N) D) and L)
O) D) and M)

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The hormone __________ induces lipolysis, whereas the hormone __________ inhibits the process.


A) epinephrine; adrenocorticotropic hormone
B) glucagon; insulin
C) insulin; norepinephrine
D) glucagon; epinephrine
E) epinephrine; glucagon

F) C) and D)
G) B) and D)

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B

Calculate the amount of ATP generated from the total oxidation of an activated fatty acid with an acyl chain of 16 carbons.

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The pathway would generate 7 NADH and 7 ...

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Fatty acids are the building blocks of:


A) cholesterol.
B) phospholipids.
C) glycolipids.
D) B and C.
E) A, B, and C.

F) A) and C)
G) A) and B)

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What is the fate of glycerol released during lipolysis?

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The glycerol is absorbed by th...

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Which organs or tissues prefer to use ketone bodies such as acetoacetate as a fuel energy source instead of glucose?


A) the heart muscle
B) the renal cortex
C) the brain
D) A and B
E) A, B, and C

F) A) and B)
G) B) and C)

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D

What three stages are required to utilize the energy stores in adipocytes?

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Three stages of processing are required....

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Explain why animals cannot convert fatty acids to glucose.

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The synthesis of glucose via gluconeogen...

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The pathway by which an acyl CoA is degraded to acetyl CoA is ____________.


A) pyrophosphate
B) 106 ATP
C) pyruvate dehydrogenase
D) β oxidation
E) glucagon
F) glycolysis
G) 30 ATP
H) cobalamin
I) β hydroxybutyrate
J) hormone-sensitive lipase
K) oxaloacetate
L) adipose
M) acyl CoA dehydrogenase

N) D) and L)
O) B) and L)

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In eukaryotes, the degradation of fatty acids occurs in the ________________.

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mitochondr...

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How is pyrophosphate formation an important theme in biochemistry?

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The hydrolysis of inorganic pyrophosphate is a high-energy reaction that is not easily reversed. The hydrolysis of PPi drives a reversible reaction to completion. Essentially, two phosphoanhydride bonds are used to drive an energetically unfavorable reaction. It is a common strategy in several paths.

Odd-numbered unsaturated fatty acids are metabolized by which of the following enzymes?


A) propionyl CoA carboxylase
B) 2,4-dienoyl reductase
C) enoyl-CoA isomerase
D) All of the above.
E) None of the above.

F) A) and B)
G) B) and D)

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